• Hydroxyurea Use Associated with Nonverbal and Executive Skills in Sickle Cell Anemia

    3 days ago - By Journal of Pediatric Psychology

    AbstractObjectiveHydroxyurea is used in children with sickle cell disease to increase fetal hemoglobin , contributing to a decrease in physical symptoms and potential protection against cerebral microvasculopathy. There has been minimal investigation into the association between HU use and cognition in this population. This study examined the relationship between HU status and cognition in children with SCD.MethodsThirty-seven children with SCD HbSS or HbS/β 0 thalassaemia ages 4:0-11 years with no history of overt stroke or chronic transfusion completed a neuropsychological test battery...
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  • Feasibility of Medical Student Mentors to Improve Transition in Sickle Cell Disease

    3 days ago - By Journal of Pediatric Psychology

    AbstractObjectiveAdvances in medical care have resulted in nearly 95% of all children with sickle cell disease living to adulthood. There is a lack of effective transition programming, contributing to high rates of mortality and morbidity among adolescents and young adults during the transition from pediatric to adult healthcare. This nonrandomized study evaluated the feasibility, acceptability, and preliminary outcomes of a novel medical student mentor intervention to improve transition outcomes for AYA with SCD.MethodsEligible participants were ages 18-25 years, either preparing for...
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  • Sickle Cell Disease, Trait May Up Risk for Poor COVID Outcomes

    3 days ago - By Medscape

    The risk for hospitalization quadrupled and mortality risk doubled in a cohort of patients with sickle cell disease; excess risk was also seen among carriers, but the magnitude was smaller.
    Medscape Medical News
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