Fat grafting: Early hypoxia, oxidative stress, and inflammation developing prior to injection
One year ago - By Journal of Plastic, Reconstructive & Aesthetic Surgery
Autologous fat grafting is widely used during plastic surgery but unpredictable fat retention remains a major concern. Although many studies have explored whether fat harvesting, processing, and injection affect adipocyte viability, the oxygenation and inflammatory status of grafted fat remain unknown. Unlike vascularized tissue transfer, fat grafting is a non-vascular procedure. Fat initially lacks vascular support and receives oxygen and nutrients only via diffusion until neovascularization develops.
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