• Adolescent Binge Drinking Impacts Adult Behavior

    10 days ago - By Medindia Health

    New study examines how teenagers' binge drinking affects genes, brain circuitry, behaviors through epigenetics that alter the expression of genes without directly modifying them.
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  • Brain α-Tocopherol Concentration and Stereoisomer Profile Alter Hippocampal Gene Expression in Weanling Mice

    Brain α-Tocopherol Concentration and Stereoisomer Profile Alter Hippocampal Gene Expression in Weanling Mice

    10 days ago - By Nutrition

    ABSTRACTBackgroundAlpha-tocopherol , the bioactive constituent of vitamin E, is essential for fertility and neurological development. Synthetic αT is added to infant formula at higher concentrations than natural αT to adjust for bio-potency differences, but its effects on brain development are poorly understood.ObjectivesThe objective was to determine the impact of bio-potency-adjusted dietary all rac-αT versus RRR-αT, fed to dams, on the hippocampal gene expression in weanling mice.MethodsMale/female pairs of C57BL/6J mice were fed AIN 93-G containing RRR-αT or all rac-αT at 37.5 or 75...
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