• Rats Self-Select a Constant Protein-to-Carbohydrate Ratio Rather Than a Constant Protein-to-Energy Ratio and Have Low Plasma FGF21 Concentrations

    12 days ago - By Nutrition

    ABSTRACTBackgroundUnder dietary self-selection , rats ingest 25-30% of energy as protein. This high level appears to be explained by metabolic benefits related to reduced carbohydrate dependence and associated pathologies. However, the mechanisms underlying these choices remain largely misunderstood.ObjectivesThe aim was to test the hypothesis that in a DSS model, rats select a protein-to-energy ratio to maintain the protein-to-carbohydrate ratio constant and that fibroblast growth factor 21 is involved in this response.MethodsAdult male Wistar rats were used in 3 experiments. The first...
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