• Combined monogenic, polygenic risk prediction spurs changes in CAD management

    1 month ago - By Healio

    A combined monogenic and polygenic risk assessment for CAD can identify individuals at high inherited risk before overt manifestation of traditional risk factors, potentially improving clinician decision-making on preventive interventions.
    Clinical risk calculators such as the American College of Cardiology/American Heart Association Pooled Cohort Equations estimate 10-year atherosclerotic CVD risk to guide patient risk discussion around initiating statin therapy to lower LDL, Akl C. Fahed, MD, MPH, FACC, an interventional cardiologist and physician-scientist at Massachusetts General Hospital
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