• Emerging SARS-CoV-2 mutations L452R & Y453F evade cellular immunity

    2 days ago - By News Medical

    The study, published in the journal Cell Host & Microbe, also showed emerging mutations L452R and Y453F in the SARS-CoV-2 spike receptor-binding motif evade A24-restricted cellular immunity. Meanwhile, the L452R enhances spike stability, viral fusogenicity, and viral infectivity. Hence, the findings suggest that HLA-restricted cellular immunity potentially affects the evolution of viral phenotypes.
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  • Existing Drug Found to Inhibit SARS-CoV-2 Virus

    Existing Drug Found to Inhibit SARS-CoV-2 Virus

    2 days ago - By Medindia Health

    Drug Masitinib may be effective in treating COVID-19, as per the new Chicago study.
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  • Scientist explore conserved RNA elements as potential targets for anti-SARS-CoV-2 drugs

    2 days ago - By News Medical

    The study, published in the journal Angewandte Chemie International Edition, identified many small molecules that bind to certain parts of the SARS-CoV-2 genome that are less likely altered by mutations using dedicated substance libraries. The scientists derived key functional units and groups in ligands for effective and safe targeting of SARS-CoV-2 RNA.
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