• Selenium Status Affects Hypertrophic Growth of Skeletal Muscle in Growing Zebrafish by Mediating Protein Turnover

    2 monthes ago - By Journal of Nutrition

    ABSTRACTBackgroundSelenium status is closely related to skeletal muscle physiological status. However, its influence on skeletal muscle growth has not been well studied.ObjectivesThis study aimed to analyze the impacts of overall Se status on skeletal muscle growth using a growing zebrafish model.MethodsZebrafish were fed graded levels of Se (deficient: 0.10 mg Se/kg; marginally deficient: 0.22 mg Se/kg; adequate: 0.34 mg Se/kg; high: 0.44, 0.57, and 0.69 mg Se/kg) as Se-enriched yeast for 30 d. Zebrafish growth, and Se accumulation, selenoenzyme activity, selenotranscriptome profiles, and...
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