• Dihydromyricetin Imbues Antiadipogenic Effects on 3T3-L1 Cells via Direct Interactions with 78-kDa Glucose-Regulated Protein

    6 days ago - By Nutrition

    ABSTRACTBackgroundObesity is among the most serious public health problems worldwide, with few safe pharmaceutical interventions. Natural products have become an important source of potential anti-obesity therapeutics. Dihydromyricetin exerts antidiabetic effects. The biochemical target of DHM, however, has been unknown. It is crucial to identify the biochemical target of DHM for elucidating its physiological function and therapeutic value.ObjectivesThe objective of this study was to identify the biochemical target of DHM.MethodsAn abundant antiadipogenic flavanonol was extracted from the...
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