• Analgesic Efficacy of Intranasal Ketamine Versus Intranasal Fentanyl for Moderate to Severe Pain in Children: A Prospective, Randomized, Double-Blind Study

    6 days ago - By Pediatric Emergency Care

    Purpose
    This study aimed to compare analgesic efficacy of intranasal ketamine to IN fentanyl for moderate to severe pain in children in a pediatric emergency department.
    Methods
    A prospective, randomized, double-blinded, noninferiority study evaluating children aged 3 to 17 years in a pediatric emergency department with acute moderate to severe pain was conducted. Patients received either 1 mg/kg of IN ketamine or 1.5 μg/kg of IN fentanyl and were evaluated after 10, 20, 30, and 60 minutes. The primary outcome was the degree of pain reduction after 20 minutes.
    Results
    Twenty-two patients...
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