• Adverse pregnancy outcomes more common when isoniazid initiated during pregnancy

    1 day ago - By Healio

    The risk for adverse pregnancy outcomes is higher among women with HIV who initiate isoniazid preventive therapy for tuberculosis during pregnancy compared with those who initiate it after delivery, study data confirmed.
    Past research demonstrated a greater risk for treatment-related adverse events among mothers who initiated isoniazid treatment during pregnancy, suggesting that the best time to start isoniazid is after delivery.
    In the IMPAACT P1078 study, a randomized noninferiority study, Gerard Theron, MD, head of the department of obstetrics and gynecology at Stellenbosch University, and
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