• Combination treatment for methamphetamine use disorder shows promise

    13 days ago - By ScienceDaily

    A combination of two medications, injectable naltrexone and oral bupropion, was safe and effective in treating adults with moderate or severe methamphetamine use disorder in a double-blind, placebo-controlled Phase III clinical trial. The findings suggest this combination therapy may be a promising addition to current approaches to treatment, such as cognitive behavioral therapy and contingency management interventions, for a very serious condition that remains difficult to treat and overcome.
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  • Naltrexone and Bupropion Promising Combo for Meth Addiction

    13 days ago - By Medscape

    The combination treatment may be a game changer for some patients with severe methamphetamine use disorder, results of a new randomized trial, ADAPT-2, suggest.
    Medscape Medical News
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  • Naltrexone-bupropion more effective than placebo for methamphetamine use disorder

    13 days ago - By Healio

    Responses to combination naltrexone-bupropion therapy among adults with methamphetamine use disorder were “low” but higher than responses to placebo, researchers reported.
    Currently, there are no FDA-approved treatments for methamphetamine use disorder, according to Madhukar H. Trivedi, MD, a professor in the department of psychiatry at the University of Texas Southwestern Medical Center, and colleagues.
    “Long-term methamphetamine misuse has been shown to cause diffuse changes to the brain, which can contribute to severe health consequences beyond addiction itself,”
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  • Naltrexone-Bupropion Helps for Meth Addiction, But Not a Lot

    Naltrexone-Bupropion Helps for Meth Addiction, But Not a Lot

    13 days ago - By MedPageToday

    A combination of naltrexone and bupropion was helpful in slightly reducing drug use for those struggling with methamphetamine use disorder, according to a double-blind, placebo-controlled study.
    During the 12-week trial, 13...
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