VEGA: Guselkumab plus golimumab achieved higher clinical remission rates in UC
12 days ago - By Healio
CHARLOTTE, N.C. - Guselkumab in combination with golimumab induced greater rates of clinical remission compared with monotherapy among patients with moderate to severely active ulcerative colitis.
VEGA phase 2a proof-of-concept week 12 data showed dual blockade of interleukin -23 and tumor necrosis factor induced clinical response, clinical remission, endoscopic improvement and composite histologic-endoscopic outcomes more effectively than monotherapy alone, Brian G. Feagan, MD, senior scientific director of Alimentiv Inc. and gastroenterologist at Western University, reported at the
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