• VITAL: Vitamin D, omega-3 fail to reduce major CV events, cancer

    10 days ago - By Healio

    CHICAGO - In the large-scale VITAL trial, neither omega-3 nor vitamin D supplements for primary prevention reduced major CV events or development of invasive cancers compared with placebo over 5 years of follow-up.
    The 25,871-patient, placebo-controlled trial had a 2x2 factorial design, by which patients were randomly assigned vitamin D3 2,000 IU per day and omega-3 fatty acids 1 g per day, each compared with placebo.
    VITAL had two primary endpoints: major CV events, defined as a composite of MI, stroke or death from CV causes, and invasive cancer of any type. Patients
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